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Cleanroom: How It Differs

In the architectural layout of cleanrooms, an annular sealed corridor is generally set outside the workshop. It provides a buffer zone between the clean area and the outside world. It can prevent external pollution and is relatively energy-saving. 

The Cleanroom doors and windows in the plant should be flat on the inner wall and no window sills should be installed. The number of layers and the structure of the outer window should be fully considered to seal the air moisture, so that the pollutant particles are not easy to penetrate from the outside.


In order to prevent condensation caused by the temperature difference between indoor and outdoor, the gaps between doors and windows between rooms with different cleanliness should be sealed. Door and window materials should be selected for good weather resistance, small natural deformation, small manufacturing errors, good air tightness, simple shape, not easy to accumulate dust, easy to clean, and no threshold for door frames. 

The doors and windows of the cleanroom should be made of metal or metal-coated materials, and wooden doors and windows should not be used to avoid long-term moisture and bacteria. The windows on the outer wall should be level with the inner wall, the window sill should be angled or no window sill should be left, and the double fixed window should be used to reduce energy loss.

The ground should be flat, seamless, corrosion-resistant, not easy to accumulate static electricity, and easy to clean. In-situ terrazzo ground can be used in the design, and the diameter of the stones used should be between 6-15mm. 

Among them, the divider bars are separated by copper bars, and glass bars are not allowed. Epoxy artesian floor is now mostly used, which is a resin composite floor. It is characterized by solvent-free, odorless, jointless, and self-leveling. Yes. Achieve mirror decoration effect, seamless connection, oil resistance and acid, alkali, salt chemical solvents. It has the characteristics of low dust generation and impact resistance, but the cost is high. Most of them are used on the floors of production workshops in electronics, medicine, blood products and other industries that require high cleanliness, beautiful appearance, dust-free, and sterile.

 The service life of epoxy artesian floor is more than 1mm and can be used for more than 6 years. A moisture-proof layer should be laid under the above-mentioned floor cushion, and the concrete compartment should not pass through the clean area.

The wall surface should be smooth, flat and dust-free, corrosion-resistant, harmonious in color, and easy to identify pollutants. The interior wall paint should be painted with materials that avoid glare and can withstand cleaning and disinfection. 

The intersection of the wall and the ground should be an arc with a radius of 50 mm to reduce dust accumulation and facilitate cleaning. Anti-collision railings should be installed on the walls of the transportation corridors and other vulnerable places to prevent the dust from falling off due to the vibration of the decoration materials.

In order to ensure the clean room, all air supply pipes and lamps are arranged in the technical mezzanine. Most pharmaceutical companies now use color steel sandwich panels to seal their ceilings. The color steel sandwich panel has the characteristics of light weight, high overall strength, good integrity, and low dust generation. It is more suitable for ISO production plants.

However, the fixed ceiling is connected to the main body of the structure and cannot be mixed with equipment and pipe supports. The ceiling and the wall should be smoothly connected. The ceiling and the return air duct should be reliably closed. After the ceiling installation is completed, light inspection should be carried out to ensure that there is no gap. 

According to process requirements, maintenance walkways should generally be provided in the technical interlayer to facilitate pipeline maintenance and filter replacement. The walls and ceiling of the technical mezzanine need to be painted.

In addition, strict requirements should be imposed on the pipe penetration of electrical circuits, and steel pipes should be used where possible to ensure that electrical circuits do not become a way for fire to spread.

In summary, the clean room has higher requirements for air temperature, humidity and cleanliness. Designers should select construction materials reasonably according to process requirements and production cleanliness, and consider fire resistance, so as to meet ISO design requirements.

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